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Role of single-channel stochastic noise on bursting clusters of pancreatic beta-cells.

To study why pancreatic beta-cells prefer to burst as a multi-cellular complex, we have formulated a stochastic model for bursting clusters of excitable cells. Our model incorporated a delayed rectifier K+ channel, a fast voltage-gated Ca2+ channel, and a slow Cai-blockable Ca2+ channel. The fractio...

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Bibliographic Details
Main Authors: Chay, T R, Kang, H S
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1330342/
https://ncbi.nlm.nih.gov/pubmed/2850030
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