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Modification of sodium and gating currents by amino group specific cross-linking and monofunctional reagents.

To test the possible role of lysine residues in Na channel function the effects of several imidoesters on Na and gating currents were studied in voltage-clamped single frog nerve fibers. Mono- and bisimidoesters were used. These reagents modify amino groups exclusively and do not change the net char...

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Detalles Bibliográficos
Main Authors: Drews, G, Rack, M
Formato: Artigo
Idioma:Inglês
Publicado: 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1330337/
https://ncbi.nlm.nih.gov/pubmed/2850028
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