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A Glycoconjugate Vaccine for Neisseria meningitidis Induces Antibodies in Human Infants That Afford Protection against Meningococcal Bacteremia in a Neonate Rat Challenge Model

The functional activities of serum samples from human infants immunized with a glycoconjugate vaccine for Neisseria meningitidis serogroup C were assessed in a complement-mediated antibody-dependent serum bactericidal assay (SBA) and in a neonate rat model of protection from bacteremia. Selective se...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Mountzouros, Kenneth T., A. Belanger, Kelly, P. Howell, Alan, Bixler, Jr., Garvin S., Madore, Dace V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.12.6576-6582.2002
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