Genetic Requirements for Salmonella-Induced Cytopathology in Human Monocyte-Derived Macrophages

Infection of human macrophages with Salmonella enterica serovar Typhimurium or Salmonella enterica serovar Dublin produces delayed cytotoxicity characterized by cell detachment and associated apoptosis. Using a site-specific mutant in the SpvB active site, we verify that the ADP-ribosylation activit...

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Detalhes bibliográficos
Main Authors: Browne, Sara H., Lesnick, Marc L., Guiney, Donald G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133012/
https://ncbi.nlm.nih.gov/pubmed/12438395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.7126-7135.2002
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