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A test of the stochastic theory of stem cell differentiation.
Stochastic theories of stem cell renewal are shown to predict turnover of intestinal crypts. While I found ample evidence of production of new crypts from direct in vivo studies in adult mice, I failed to find evidence of crypt loss. Thus, it would appear that the simple stochastic models may not pr...
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Hoofdauteur: | |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
1986
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1329706/ https://ncbi.nlm.nih.gov/pubmed/3719076 |
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