Pharmacokinetics and Efficacies of Liposomal and Conventional Formulations of Tobramycin after Intratracheal Administration in Rats with Pulmonary Burkholderia cepacia Infection

The objective of the present study was to determine the pharmacokinetics and efficacies of liposomal and conventional formulations of tobramycin against Burkholderia cepacia in a model of chronic lung infection. Male Sprague-Dawley rats were inoculated intratracheally with 10(6) CFU of a very resist...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Marier, Jean-Francois, Lavigne, Jean, Ducharme, Murray P.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3776-3781.2002
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