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Voltage-dependent conductance induced by alamethicin-phospholipid conjugates in lipid bilayers.

Alamethicin, a linear 20-amino acid antibiotic, forms voltage-dependent channels in lipid bilayer membranes. We show here that alamethicin-phospholipid conjugates can be prepared by photolysis of unilamellar vesicles containing alamethicin and a phosphatidylcholine analogue with a carbene precursor...

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Bibliographic Details
Main Authors: Latorre, R, Miller, C G, Quay, S
Format: Artigo
Language:Inglês
Published: 1981
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327661/
https://ncbi.nlm.nih.gov/pubmed/7326333
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