Ex Vivo Pharmacodynamics of Amoxicillin-Clavulanate against β-Lactamase-Producing Escherichia coli in a Yucatan Miniature Pig Model That Mimics Human Pharmacokinetics

The objective of the present study was to investigate the potential bactericidal activity of amoxicillin-clavulanate against β-lactamase-producing Escherichia coli strains and to elucidate the extent to which enzyme production affects the activity. Six adult Yucatan miniature pigs received a single...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Bronner, Stéphane, Murbach, Valérie, Peter, Jean-Daniel, Levêque, Dominique, Elkhaïli, Hassan, Salmon, Yves, Dhoyen, Nathalie, Monteil, Henri, Woodnutt, Gary, Jehl, François
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Experimental Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132757/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3782-3789.2002
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