Synthetic Analogues of β-1,2 Oligomannosides Prevent Intestinal Colonization by the Pathogenic Yeast Candida albicans

The pathogenic yeast Candida albicans displays at its cell surface β-1,2 oligomannosides (β-1,2-Mans). In contrast to the ubiquitous α-Mans, β-1,2-Mans bind to galectin-3, a major endogenous lectin expressed on epithelial cells. The specific role of β-1,2-Mans in colonization of the gut by C. albica...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Dromer, Françoise, Chevalier, Reynald, Sendid, Boualem, Improvisi, Luce, Jouault, Thierry, Robert, Raymond, Mallet, Jean Maurice, Poulain, Daniel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3869-3876.2002
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