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Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p

The yeast ubiquitin-protein ligase Rsp5p regulates processes as diverse as polII transcription and endocytosis. Here, we identify Rsp5p in a screen for tRNA export (tex) mutants. The tex23-1/rsp5-3 mutant, which is complemented by RSP5, not only shows a strong nuclear accumulation of tRNAs at the re...

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Détails bibliographiques
Auteurs principaux: Neumann, Silvia, Petfalski, Elisabeth, Brügger, Britta, Großhans, Helge, Wieland, Felix, Tollervey, David, Hurt, Ed
Format: Artigo
Langue:Inglês
Publié: 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326418/
https://ncbi.nlm.nih.gov/pubmed/14608372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400026
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