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Exclusion of exogenous phosphatidylinositol-3,4,5-trisphosphate from neutrophil-polarizing pseudopodia: stabilization of the uropod and cell polarity

Although there is accumulating evidence that the generation and localization of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) have important functions in neutrophil polarization and chemotaxis, the mechanism of this linkage has yet to be established. Here, using exogenous fluorescent...

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Autores principales: Tian, Wei, Laffafian, Iraj, Dewitt, Sharon, Hallett, Maurice B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326405/
https://ncbi.nlm.nih.gov/pubmed/14528267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor947
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