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Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor

Lassa virus glycoprotein is translated as a precursor (pre-GP-C) into the lumen of the endoplasmic reticulum and is cotranslationally cleaved into the signal peptide and GP-C, before GP-C is proteolytically processed into its subunits GP1 and GP2. The signal peptide of pre-GP-C comprises 58 amino ac...

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Detalhes bibliográficos
Main Authors: Eichler, Robert, Lenz, Oliver, Strecker, Thomas, Eickmann, Markus, Klenk, Hans-Dieter, Garten, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326372/
https://ncbi.nlm.nih.gov/pubmed/14555961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400002
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