Llwytho...
The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing.
The semaphorins are a large group of cell surface and secreted proteins implicated in axonal pathfinding. Here we show that the secreted mouse semaphorin D (SemD) is synthesized as an inactive precursor (proSemD) and becomes repulsive for sensory and sympathetic neurites upon proteolytic cleavage. P...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
1997
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326291/ https://ncbi.nlm.nih.gov/pubmed/9321387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.20.6077 |
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