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High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
Telomerase is essential to maintain telomere length in most eukaryotes. Other functions for telomerase have been proposed but molecular mechanisms remain unclear. We studied Caenorhabditis elegans with a mutation in the trt-1 telomerase reverse transcriptase gene. Mutant animals showed a progressive...
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Autores principales: | , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326242/ https://ncbi.nlm.nih.gov/pubmed/16407328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj417 |
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