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Hypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes

RNA polymerase (pol) III transcription decreases when primary cultures of rat neonatal cardiomyocytes are exposed to low oxygen tension. Previous studies in fibroblasts have shown that the pol III-specific transcription factor IIIB (TFIIIB) is bound and regulated by the proto-oncogene product c-Myc,...

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Detalhes bibliográficos
Main Authors: Ernens, Isabelle, Goodfellow, Sarah J., Innes, Fiona, Kenneth, Niall S., Derblay, Louise E., White, Robert J., Scott, Pamela H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326236/
https://ncbi.nlm.nih.gov/pubmed/16407335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj402
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