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Absence of mutations in the coding sequence of the potential tumor suppressor 3pK in metastatic melanoma

BACKGROUND: Activation of Ras or Raf contributes to tumorigenesis of melanoma. However, constitutive Raf activation is also a characteristic of the majority of benign melanocytic nevi and high intensity signaling of either Ras or Raf was found to induce growth inhibition and senescence rather than t...

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Autores principales: Houben, Roland, Becker, Jürgen C, Rapp, Ulf R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326198/
https://ncbi.nlm.nih.gov/pubmed/16367997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-4-23
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