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Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration
Plasmid-mediated gene therapy can restore dystrophin expression in skeletal muscle in the mdx mouse, a model of Duchenne muscular dystrophy. However, sufficient long-term expression and distribution of dystrophin remain a hurdle for translating this technology into a viable treatment for Duchenne mu...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326153/ https://ncbi.nlm.nih.gov/pubmed/16387861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504505102 |
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