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Type 3 deiodinase is critical for the maturation and function of the thyroid axis

Developmental exposure to appropriate levels of thyroid hormones (THs) in a timely manner is critical to normal development in vertebrates. Among the factors potentially affecting perinatal exposure of tissues to THs is type 3 deiodinase (D3). This enzyme degrades THs and is highly expressed in the...

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Detalhes bibliográficos
Main Authors: Hernandez, Arturo, Martinez, M. Elena, Fiering, Steven, Galton, Valerie Anne, St. Germain, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326144/
https://ncbi.nlm.nih.gov/pubmed/16410833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26240
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