Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice

BACKGROUND: Analysis of an allelic series of point mutations in a gene, generated by N-ethyl-N-nitrosourea (ENU) mutagenesis, is a valuable method for discovering the full scope of its biological function. Here we present an efficient gene-driven approach for identifying ENU-induced point mutations...

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Hlavní autoři: Michaud, Edward J, Culiat, Cymbeline T, Klebig, Mitchell L, Barker, Paul E, Cain, KT, Carpenter, Debra J, Easter, Lori L, Foster, Carmen M, Gardner, Alysyn W, Guo, ZY, Houser, Kay J, Hughes, Lori A, Kerley, Marilyn K, Liu, Zhaowei, Olszewski, Robert E, Pinn, Irina, Shaw, Ginger D, Shinpock, Sarah G, Wymore, Ann M, Rinchik, Eugene M, Johnson, Dabney K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325271/
https://ncbi.nlm.nih.gov/pubmed/16300676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-164
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