Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism

BACKGROUND: The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function. METHODS: The gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK-C) was deleted in mice by...

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Main Authors: Hakimi, Parvin, Johnson, Mark T, Yang, Jianqi, Lepage, David F, Conlon, Ronald A, Kalhan, Satish C, Reshef, Lea, Tilghman, Shirley M, Hanson, Richard W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325233/
https://ncbi.nlm.nih.gov/pubmed/16300682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-2-33
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