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Mapping of orthologous genes in the context of biological pathways: An application of integer programming

Mapping biological pathways across microbial genomes is a highly important technique in functional studies of biological systems. Existing methods mainly rely on sequence-based orthologous gene mapping, which often leads to suboptimal mapping results because sequence-similarity information alone doe...

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Main Authors: Mao, Fenglou, Su, Zhengchang, Olman, Victor, Dam, Phuongan, Liu, Zhijie, Xu, Ying
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325003/
https://ncbi.nlm.nih.gov/pubmed/16373500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509737102
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