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Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: A HEAT-repeat-containing metalloenzyme

The eukaryotic initiation factor 5A (eIF5A), a factor essential for eukaryotic cell proliferation, is the only cellular protein containing the polyamine-derived amino acid hypusine [N(ε)-(4-amino-2-hydroxybutyl)lysine]. Hypusine is formed in a posttranslational modification that involves two sequent...

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Detalhes bibliográficos
Main Authors: Park, Jong-Hwan, Aravind, L., Wolff, Edith C., Kaevel, Jörn, Kim, Yeon Sook, Park, Myung Hee
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1324997/
https://ncbi.nlm.nih.gov/pubmed/16371467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509348102
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