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Promoter Variation in the DC-SIGN–Encoding Gene CD209 Is Associated with Tuberculosis

BACKGROUND: Tuberculosis, which is caused by Mycobacterium tuberculosis, remains one of the leading causes of mortality worldwide. The C-type lectin DC-SIGN is known to be the major M. tuberculosis receptor on human dendritic cells. We reasoned that if DC-SIGN interacts with M. tuberculosis, as well...

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Detalhes bibliográficos
Main Authors: Barreiro, Luis B, Neyrolles, Olivier, Babb, Chantal L, Tailleux, Ludovic, Quach, Hélène, McElreavey, Ken, van Helden, Paul D., Hoal, Eileen G, Gicquel, Brigitte, Quintana-Murci, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1324949/
https://ncbi.nlm.nih.gov/pubmed/16379498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030020
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