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Microchimerism maintains deletion of the donor cell–specific CD8(+) T cell repertoire

Rare cases of stable allograft acceptance after discontinuation of immunosuppression are often accompanied by macrochimerism (> 1% donor cells in blood) or microchimerism (< 1% donor cells in blood). Here, we have investigated whether persistence of donor cells is the cause or the consequence...

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Detalhes bibliográficos
Main Authors: Bonilla, Weldy V., Geuking, Markus B., Aichele, Peter, Ludewig, Burkhard, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323267/
https://ncbi.nlm.nih.gov/pubmed/16395404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26565
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