Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

We find that CD11c(+) cells with many markers of dendritic cells (DCs) are a major cell type in the skin lesions of psoriasis. These CD11c(+) cells, which are evident in both epidermis and dermis, are the sites for the expression of two mediators of inflammation, inducible nitric oxide synthase (iNO...

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Detalhes bibliográficos
Main Authors: Lowes, Michelle A., Chamian, Francesca, Abello, Maria Veronica, Fuentes-Duculan, Judilyn, Lin, Shao-Lee, Nussbaum, Rachel, Novitskaya, Inna, Carbonaro, Henrietta, Cardinale, Irma, Kikuchi, Toyoko, Gilleaudeau, Patricia, Sullivan-Whalen, Mary, Wittkowski, Knut M., Papp, Kim, Garovoy, Marvin, Dummer, Wolfgang, Steinman, Ralph M., Krueger, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323218/
https://ncbi.nlm.nih.gov/pubmed/16380428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509736102
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