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A cancer DNA phenotype in healthy prostates, conserved in tumors and adjacent normal cells, implies a relationship to carcinogenesis

A cancer DNA phenotype, identical to the DNA structure of tumors, has been identified in the prostate glands of certain healthy men over 55 years of age. We now show that the same DNA signature exists in normal tissues adjacent to tumors. This finding implies that the phenotype is maintained in norm...

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Detalhes bibliográficos
Main Authors: Malins, Donald C., Gilman, Naomi K., Green, Virginia M., Wheeler, Thomas M., Barker, Edward A., Anderson, Katie M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323211/
https://ncbi.nlm.nih.gov/pubmed/16361440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509630102
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