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The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes

Cryo-electron microscopy of vitreous section makes it possible to observe cells and tissues at high resolution in a close-to-native state. The specimen remains hydrated; chemical fixation and staining are fully avoided. There is minimal molecular aggregation and the density observed in the image cor...

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Detalhes bibliográficos
Main Authors: Zuber, Benoît, Nikonenko, Irina, Klauser, Paul, Muller, Dominique, Dubochet, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323199/
https://ncbi.nlm.nih.gov/pubmed/16354833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509527102
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