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Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

The bulged insertions of (R)-1-O-(pyren-1-ylmethyl)glycerol (monomer P) in two complementary 8mer DNA strands (intercalating nucleic acids) opposite to each other resulted in the formation of an easily denaturing duplex, which had lower thermal stability (21.0°C) than the wild-type double-stranded D...

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Bibliografske podrobnosti
Main Authors: Filichev, Vyacheslav V., Vester, Birte, Hansen, Lykke H., Pedersen, Erik B.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1322271/
https://ncbi.nlm.nih.gov/pubmed/16377781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki1019
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