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Efficient single nucleotide polymorphism discovery in laboratory rat strains using wild rat-derived SNP candidates

BACKGROUND: The laboratory rat (Rattus norvegicus) is an important model for studying many aspects of human health and disease. Detailed knowledge on genetic variation between strains is important from a biomedical, particularly pharmacogenetic point of view and useful for marker selection for genet...

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Detalhes bibliográficos
Main Authors: Smits, Bart MG, Guryev, Victor, Zeegers, Dimphy, Wedekind, Dirk, Hedrich, Hans J, Cuppen, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1318490/
https://ncbi.nlm.nih.gov/pubmed/16316463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-170
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