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Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells
Alcohol abuse reduces response rates to IFN therapy in patients with chronic hepatitis C. To model the molecular mechanisms behind this phenotype, we characterized the effects of ethanol on Jak-Stat and MAPK pathways in Huh7 human hepatoma cells, in HCV replicon cell lines, and in primary human hepa...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1318489/ https://ncbi.nlm.nih.gov/pubmed/16324217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-89 |
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