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Regulation of CD44 Alternative Splicing by SRm160 and Its Potential Role in Tumor Cell Invasion
The multiple isoforms of the transmembrane glycoprotein CD44 are produced by alternative RNA splicing. Expression of CD44 isoforms containing variable 5 exon (v5) correlates with enhanced malignancy and invasiveness of some tumors. Here we demonstrate that SRm160, a splicing coactivator, regulates C...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317625/ https://ncbi.nlm.nih.gov/pubmed/16354706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.362-370.2006 |
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