Distinct Utilization of Effectors and Biological Outcomes Resulting from Site-Specific Ras Activation: Ras Functions in Lipid Rafts and Golgi Complex Are Dispensable for Proliferation and Transformation

Ras proteins are distributed in different types of plasma membrane microdomains and endomembranes. However, how microlocalization affects the signals generated by Ras and its subsequent biological outputs is largely unknown. We have approached this question by selectively targeting RasV12 to differe...

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Detalhes bibliográficos
Main Authors: Matallanas, David, Sanz-Moreno, Victoria, Arozarena, Imanol, Calvo, Fernando, Agudo-Ibáñez, Lorena, Santos, Eugenio, Berciano, María T., Crespo, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317613/
https://ncbi.nlm.nih.gov/pubmed/16354683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.100-116.2006
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