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Characterization of Early Steps in the Poliovirus Infection Process: Receptor-Decorated Liposomes Induce Conversion of the Virus to Membrane-Anchored Entry-Intermediate Particles

The mechanism by which poliovirus infects the cell has been characterized by a combination of biochemical and structural studies, leading to a working model for cell entry. Upon receptor binding at physiological temperature, native virus (160S) undergoes a conformational change to a 135S particle fr...

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Main Authors: Tuthill, Tobias J., Bubeck, Doryen, Rowlands, David J., Hogle, James M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317540/
https://ncbi.nlm.nih.gov/pubmed/16352541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.172-180.2006
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