At Least 1 in 20 16S rRNA Sequence Records Currently Held in Public Repositories Is Estimated To Contain Substantial Anomalies

A new method for detecting chimeras and other anomalies within 16S rRNA sequence records is presented. Using this method, we screened 1,399 sequences from 19 phyla, as defined by the Ribosomal Database Project, release 9, update 22, and found 5.0% to harbor substantial errors. Of these, 64.3% were o...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ashelford, Kevin E., Chuzhanova, Nadia A., Fry, John C., Jones, Antonia J., Weightman, Andrew J.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2005
الموضوعات:
Environmental Microbiology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317345/
https://ncbi.nlm.nih.gov/pubmed/16332745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.12.7724-7736.2005
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