Involvement of Prep1 in the αβ T-Cell Receptor T-Lymphocytic Potential of Hematopoietic Precursors

Prep1 is a homeodomain transcription factor that acts by dimerizing with Pbx. Since Prep1 null embryos die at gastrulation, we studied Prep1(i/i) hypomorphic mice to study the physiological role of Prep1. A low percentage of homozygous Prep1(i/i) mice survived at birth, and their postnatal functions...

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Detalhes bibliográficos
Main Authors: Penkov, Dmitri, Di Rosa, Patrizia, Fernandez Diaz, Luis, Basso, Veronica, Ferretti, Elisabetta, Grassi, Fabio, Mondino, Anna, Blasi, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316969/
https://ncbi.nlm.nih.gov/pubmed/16314502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.10768-10781.2005
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