The Caenorhabditis elegans Heterochronic Regulator LIN-14 Is a Novel Transcription Factor That Controls the Developmental Timing of Transcription from the Insulin/Insulin-Like Growth Factor Gene ins-33 by Direct DNA Binding

A temporal gradient of the novel nuclear protein LIN-14 specifies the timing and sequence of stage-specific developmental events in Caenorhabditis elegans. The profound effects of lin-14 mutations on worm development suggest that LIN-14 directly or indirectly regulates stage-specific gene expression...

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Detalhes bibliográficos
Main Authors: Hristova, Marta, Birse, Darcy, Hong, Yang, Ambros, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316966/
https://ncbi.nlm.nih.gov/pubmed/16314527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.11059-11072.2005
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