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Interleukin-1 Stimulates β-Cell Necrosis and Release of the Immunological Adjuvant HMGB1
BACKGROUND: There are at least two phases of β-cell death during the development of autoimmune diabetes: an initiation event that results in the release of β-cell-specific antigens, and a second, antigen-driven event in which β-cell death is mediated by the actions of T lymphocytes. In this report,...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316065/ https://ncbi.nlm.nih.gov/pubmed/16354107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030017 |
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