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Interleukin-1 Stimulates β-Cell Necrosis and Release of the Immunological Adjuvant HMGB1

BACKGROUND: There are at least two phases of β-cell death during the development of autoimmune diabetes: an initiation event that results in the release of β-cell-specific antigens, and a second, antigen-driven event in which β-cell death is mediated by the actions of T lymphocytes. In this report,...

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Detalhes bibliográficos
Main Authors: Steer, Sarah A, Scarim, Anna L, Chambers, Kari T, Corbett, John A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316065/
https://ncbi.nlm.nih.gov/pubmed/16354107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030017
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