Respiratory Syncytial Virus-Inducible BCL-3 Expression Antagonizes the STAT/IRF and NF-κB Signaling Pathways by Inducing Histone Deacetylase 1 Recruitment to the Interleukin-8 Promoter

Respiratory syncytial virus (RSV) is a paramyxovirus that produces airway inflammation, in part by inducing interleukin-8 (IL-8) expression, a CXC-type chemokine, via the NF-κB/RelA and STAT/IRF signaling pathways. In RSV-infected A549 cells, IL-8 transcription attenuates after 24 h in spite of ongo...

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Detalhes bibliográficos
Main Authors: Jamaluddin, Mohammad, Choudhary, Sanjeev, Wang, Shaofei, Casola, Antonella, Huda, Ruksana, Garofalo, Roberto P., Ray, Sutapa, Brasier, Allan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316019/
https://ncbi.nlm.nih.gov/pubmed/16306601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15302-15313.2005
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