Vaccinia Virus Nicking-Joining Enzyme Is Encoded by K4L (VACWR035)

Vaccinia virus encodes an enzyme with DNA modifying activity that cleaves and inefficiently cross-links cruciformic DNA. This enzyme is contained within the virion, expressed at late times postinfection, and processes DNA in an energy-independent, Mg(2+) ion-independent manner. Viral nuclease activi...

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Detalhes bibliográficos
Main Authors: Eckert, Dawn, Williams, Ollie, Meseda, Clement A., Merchlinsky, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316005/
https://ncbi.nlm.nih.gov/pubmed/16306579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15084-15090.2005
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