A Homozygous Nonsense Mutation (428G→A) in the Human Secretor (FUT2) Gene Provides Resistance to Symptomatic Norovirus (GGII) Infections

Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an α(1,2)-fucosyltransferase synthesizing the...

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Detalhes bibliográficos
Main Authors: Thorven, Maria, Grahn, Ammi, Hedlund, Kjell-Olof, Johansson, Hugo, Wahlfrid, Christer, Larson, Göran, Svensson, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315998/
https://ncbi.nlm.nih.gov/pubmed/16306606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15351-15355.2005
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