Activation of the ATR Pathway by Human Immunodeficiency Virus Type 1 Vpr Involves Its Direct Binding to Chromatin In Vivo

The human immunodeficiency virus type 1 (HIV-1) protein Vpr (viral protein R) arrests cells in the G(2) phase of the cell cycle, a process that requires activation of the ATR (ataxia-telangiectasia and Rad3-related) pathway. In this study we demonstrate that the expression of Vpr does not cause DNA...

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Bibliographische Detailangaben
Hauptverfasser: Lai, Maoyi, Zimmerman, Erik S., Planelles, Vicente, Chen, Junjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315993/
https://ncbi.nlm.nih.gov/pubmed/16306615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15443-15451.2005
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