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Activation of the ATR Pathway by Human Immunodeficiency Virus Type 1 Vpr Involves Its Direct Binding to Chromatin In Vivo
The human immunodeficiency virus type 1 (HIV-1) protein Vpr (viral protein R) arrests cells in the G(2) phase of the cell cycle, a process that requires activation of the ATR (ataxia-telangiectasia and Rad3-related) pathway. In this study we demonstrate that the expression of Vpr does not cause DNA...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315993/ https://ncbi.nlm.nih.gov/pubmed/16306615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15443-15451.2005 |
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