Optimization of Meropenem Minimum Concentration/MIC Ratio To Suppress In Vitro Resistance of Pseudomonas aeruginosa

Suppression of resistance in a dense Pseudomonas aeruginosa population has previously been shown with optimized quinolone exposures. However, the relevance to β-lactams is unknown. We investigated the bactericidal activity of meropenem and its propensity to suppress P. aeruginosa resistance in an in...

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Главные авторы: Tam, Vincent H., Schilling, Amy N., Neshat, Shadi, Poole, Keith, Melnick, David A., Coyle, Elizabeth A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315965/
https://ncbi.nlm.nih.gov/pubmed/16304153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4920-4927.2005
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