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Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
The mitochondrial theory of aging proposes that reactive oxygen species (ROS) generated inside the cell will lead, with time, to increasing amounts of oxidative damage to various cell components. The main site for ROS production is the respiratory chain inside the mitochondria and accumulation of mt...
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| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1312403/ https://ncbi.nlm.nih.gov/pubmed/16332961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508886102 |
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