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Quantum dots to monitor RNAi delivery and improve gene silencing

A critical issue in using RNA interference for identifying genotype/phenotype correlations is the uniformity of gene silencing within a cell population. Variations in transfection efficiency, delivery-induced cytotoxicity and ‘off target’ effects at high siRNA concentrations can confound the interpr...

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Detalhes bibliográficos
Main Authors: Chen, Alice A., Derfus, Austin M., Khetani, Salman R., Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312364/
https://ncbi.nlm.nih.gov/pubmed/16352864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni188
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