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Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection

HIV type 1 (HIV-1) can rapidly escape from neutralizing antibody responses. The genetic basis of this escape in vivo is poorly understood. We compared the pattern of evolution of the HIV-1 env gene between individuals with recent HIV infection whose virus exhibited either a low or a high rate of esc...

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Detalhes bibliográficos
Main Authors: Frost, Simon D. W., Wrin, Terri, Smith, Davey M., Pond, Sergei L. Kosakovsky, Liu, Yang, Paxinos, Ellen, Chappey, Colombe, Galovich, Justin, Beauchaine, Jeff, Petropoulos, Christos J., Little, Susan J., Richman, Douglas D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1310509/
https://ncbi.nlm.nih.gov/pubmed/16339909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504658102
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