Altered differentiation of neural stem cells in fragile X syndrome

Fragile X syndrome, a common form of inherited mental retardation, is caused by the absence of the fragile X mental retardation protein (FMRP) due to a mutation in the FMR1 gene. We investigated the differentiation of neural stem cells generated from the brains of fmr1-knockout (KO) mice and from po...

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Huvudupphovsmän: Castrén, Maija, Tervonen, Topi, Kärkkäinen, Virve, Heinonen, Seppo, Castrén, Eero, Larsson, Kim, Bakker, Cathy E., Oostra, Ben A., Åkerman, Karl
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308923/
https://ncbi.nlm.nih.gov/pubmed/16314562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508995102
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