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Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents

We report that a lipoprotein-based nanoplatform generated by conjugating tumor-homing molecules to the protein components of naturally occurring lipoproteins reroutes them from their normal lipoprotein receptors to other selected cancer-associated receptors. Multiple copies of these targeting moieti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Gang, Chen, Juan, Li, Hui, Glickson, Jerry D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308912/
https://ncbi.nlm.nih.gov/pubmed/16306263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508677102
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