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RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-κB and is processed during apoptosis

RIP1 and its homologs, RIP2 and RIP3, form part of a family of Ser/Thr kinases that regulate signal transduction processes leading to NF-κB activation. Here, we identify RIP4 (DIK/PKK) as a novel member of the RIP kinase family. RIP4 contains an N-terminal RIP-like kinase domain and a C-terminal reg...

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Detalhes bibliográficos
Main Authors: Meylan, Etienne, Martinon, Fabio, Thome, Margot, Gschwendt, Michael, Tschopp, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308326/
https://ncbi.nlm.nih.gov/pubmed/12446564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf236
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