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Possible explanations for the differences in secretory characteristics between conjugated and free bile acids.
1. The hepatic extraction fraction and maximum excretory rate of conjugated cholate are greater than those of free cholate (studied after acute taurine depletion); the possibility that this difference might be due to greater bile-to-blood back-diffusion of un-ionized cholic acid (pKa 5-5) compared t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1977
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307852/ https://ncbi.nlm.nih.gov/pubmed/16125 |
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