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Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter

In mammals, growth-dependent regulation of rRNA synthesis is brought about by the transcription initiation factor TIF-IA. TIF-IA is associated with a fraction of the TBP-containing factor TIF-IB/SL1 and the initiation-competent form of RNA polymerase I (Pol I). We investigated the mechanisms that do...

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Autori principali: Yuan, Xuejun, Zhao, Jian, Zentgraf, Hanswalter, Hoffmann-Rohrer, Urs, Grummt, Ingrid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307603/
https://ncbi.nlm.nih.gov/pubmed/12393749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf212
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